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Male patient, born in 1942

2018: squamous cell carcinoma (p16+) of the tongue, cT2 cN2b M1 (lung), stage IVC à palliative chemotherapy (carboplatin – 5FU – cetuximab, followed by cetuximab maintenance)

Arterial hypertension (treated)

October 2019: follow-up cervico-thoraco-abdominal CT

à oncological disease: stable

à new right hydronephrosis, to be linked to a circumferential peri-arterial thickening (around right common iliac artery),

à 1st biopsy, 23.01.2020 (peri-iliac transvascular biopsy, NOT SHOWN): fibro-adipous tissue, without any detectable lesion nor inflammation.

Preserved renal function, no hemodynamic consequences, no significant results on immunological work-up that was performed (details not provided) à watchful waiting, with radiological follow-up

CT / PET-CT March 2020, September 2020, January 2021: partial regression of peri-iliac thickening, slow progression of peri-aortic thickening, with heterogeneous increase in metabolic activity.

à 2nd biopsy, 18.02.2021 (needle core biopsies, SLIDE PROVIDED)